Hexokinase type I multiplicity in human erythrocytes

Hexokinase type I multiplicity in human erythrocytes.

Hexokinase I in human erythrocytes exists in multiple molecular forms that differ in isoelectric points. By means of Western blotting and immunodetection of total glucose-phosphorylating activity by using an antibody raised in rabbit against homogeneous human placenta hexokinase I, a single protein band was detected. Identical results were also obtained by immunoaffinity chromatography of the p...

alteration in membrane protein, antioxidant status and hexokinase activity in erythrocytes of ccl4- induced cirrhotic rats.

several studies have shown that hepatocyte membrane composition changes in patients with cholestasis and cirrhosis. these alterations that are because of intracellular oxidative stress are supposed to be reflected in erythrocyte membrane. the aim of this study was to investigate the modification of erythrocyte membrane along with hexokinase and antioxidant enzymes during development of cirrhosi...

Human T Lymphotropic Virus Type I (HTLV-I) is a Risk Factor for Coronary Artery Disease

Energy metabolism in human erythrocytes. I. Effects of sodium fluoride.

Exposure of red cells to fluoride produces a variety of metabolic alterations, most of which are based upon the secondary effects of enolase inhibition, which reduces pyruvate synthesis and interferes with the regeneration of diphosphopyridine nucleotide (NAD). Adenosine triphosphate (ATP) is consumed in the hexokinase and phosphofructokinase reactions but is not regenerated since the deficienc...

Human T-lymphotropic Virus Type I (HTLV-I) Proviral Load and Clinical Features in Iranian HAM/TSP Patients